| 期刊詳細資料 Journal detailed information |
| 作者(Author) | Chen-Chung Liu , Chun-Houh Chen , Hai-Gwo Hwu , Shang-Ying Shiu ,
Mau-Sun Hua, Chen-Hsin Chen, Tzung-Jeng Hwang, Chih-Min Liu,
Ming H. Hsieh, Shi-Kai Liu, Wei J. Chen |
| 篇名(Article title) | Medium-term course and outcome of schizophrenia
depicted by the sixth-month subtype after an acute
episode |
| 期刊名(Journal name) | Journal of the Formosan Medical Association |
| 國際期刊(International Journal) | SCI |
| 中文摘要(Abstrct) | |
| ABSTRCT | Background/Purpose: The intermediate course of schizophrenia is a complex intertwined with
the heterogeneity of the illness. This article attempts to simplify this complexity using a hypothetical
tripartite based on the profile of symptoms at 6 months after acute treatment.
Methods: This is a prospective 5-year follow-up study including 163 schizophrenic inpatients in
northern Taiwan comparing patients’ demographic data at index admission, scores on the Positive
and Negative Syndrome Scale (PANSS) for schizophrenia and social function scale
measured at admission, 6-month follow-up, and annually, and scores on a neuropsychologic
test battery measured approximately 5 years after recruitment.
Results: Patients were grouped into three subtypes based on their sixth-month symptomatology
by Generalized Association Plots, designated as remitted (RM), persistent delusion/
hallucination (PDH), and markedly blunting (MB) groups. These three subtypes presented with
similar positive symptom profiles at recruitment, yet during follow-up, the PDH group tended
to maintain the highest risk of having worse clinical symptomatology, social functioning, and
neuropsychologic functioning, and the RM was the best outcome group.
|
| 中文關鍵字(Keyword) | |
| KEYWORD | course and outcome;
neurocognition;
schizophrenia;
social functioning;
subtype;
symptomatology |
| 卷期(Volume No) | Vol. 111 No. 5 |
| 頁數(Page number) | pp. 265~274 |
| 年份(Year) | 2012 |
| 語言(Language) | 英文 English |